Aminocaproic acid injection, usp is a 6aminohexanoic acid, which acts as an inhibitor of fibrinolysis. Antifibrinoliticos e cirurgia cardiaca com circulacao. Antifibrinolytic therapy with aminocaproic acid for the control of bleeding in thrombocytopenic patients. You can manage this and all other alerts in my account. The effect of epsilon aminocaproic acid on blood loss in patients who. Pdf valor del acido epsilon aminocaproico en anestesia. Influencia do acido epsilon aminocaproico no sangramento e na hemotransfusao posoperatoria em cirurgia.
Ahx, or 6aminohexanoic acid is a derivative and analogue of the amino acid lysine, which makes it an effective inhibitor for enzymes that bind that particular residue. The effect of epsilon aminocaproic acid on blood loss in patients who undergo primary total hip replacement. Antifibrinoliticos, acido epsilon aminocaproico, anestesia. It is a synthetic lysine that targets the lysine binding site of plasminogen, preventing its binding to fibrin and conversion into plasmin. Valor del acido epsilon aminocaproico en anestesia cardiovascular. Aminocaproic acid injection, usp, for intravenous administration, is a sterile pyrogenfree solution containing 250 mgml of aminocaproic acid and water for injection. Pdf the persistent bleeding after the extracorporeal circulation is one of the most frequent complications in cardiovascular surgery and implies the.
Epsilon aminocaproic acid eaca myopathy article pdf available in postgraduate medical journal 55642. Hard on the heels of advances in understanding of the pathogenesis of. Aminocaproic acid is soluble in water, acid and alkaline solutions. Aminocaproico acido embarazo en estudios animales ha producido dano fetal y no hay estudios adecuados en mujeres embarazadas.
Such enzymes include proteolytic enzymes like plasmin, the enzyme responsible for fibrinolysis. Value of the aminocaproic epsilon acid in pediatric cardiovascular anesthesia. The solution contains no bacteriostat or antimicrobial agent and is. Epsilonaminocaproic acid influence in bleeding and.
49 691 1059 1136 1092 1083 715 1278 631 1614 694 228 203 1538 281 330 487 1466 345 1035 1375 239 503 758 1131 881 1330 1236 90 351 115 1189 1451 31 1173